The Autonomic Nervous System: Its Study and The Pathogenesis of Chagas' Cardioneuromyopathy*
نویسنده
چکیده
INTRODUCTION American trypanosomiasis, or Chagas' disease, is one of the most frequent causes of congestive heart failure and sudden death in the world (1-4). Its pathogenesis is still a matter of debate, even though the disease was described by the Brazilian Carlos Chagas in 1909 (5,6). In 1913 this brilliant scientist already saw "a new frontier of nervous system pathology" (7), yet today the neuropathogenic nature of the disease continues to be debated, as well as the question of how it should be treated. This paper will hereafter refer to the "neurogenic theory" of Chagas' disease, as opposed to the competing "myogenic theory", which is espoused by many researchers.
منابع مشابه
Pathogenesis of cardiac neuro-myopathy in Chagas' disease and the role of the autonomic nervous system.
Millions of people in Latin America are affected by Chagas' disease. Because of its lengthy evolution its symptoms begin to be noticed in the third decade when the person is in the fullness of life. From Mexico to Argentina, Chagas' disease is an endemic cardioneuromyopathy and the population exposed to the disease is about 65 million people [1]. The disease is transmitted: (a) by trypanosome i...
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